Colospa (Mebeverine) acts directly on the smooth muscle in the gut causing it to relax. It also prevents nerve signals getting through to the muscle in the intestines. This also causes the muscle to relax, preventing painful muscle spasm. Little or no antispasmodic effect was seen on the uterus and the bronchial muscles. Gastric emptying time and intestinal propulsion were affected much less than by papaverine. No significant inhibition of normal peristalsis has been observed.
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Common uses This medicine acts directly on the smooth muscle in the gut causing it to relax. It also prevents nerve signals getting through to the muscle in the intestines. This also causes the muscle to relax, preventing painful muscle spasm. Little or no antispasmodic effect was seen on the uterus and the bronchial muscles. Gastric emptying time and intestinal propulsion were affected much less than by papaverine. No significant inhibition of normal peristalsis has been observed. Primary irritable colon characterised by persistent diarrhoea, alternating constipation and diarrhoea, abdominal pain and postprandial distension. Secondary irritable colon due to organic lesions such as regional enteritis, diverticulitis, specific and non-specific inflammatory conditions of the gastro-intestinal tract.
Directions 135 mg Colospa hydrochloride (1 tablet) 3 times daily, preferably before meals. After a period of a few weeks when the desired effect has been obtained, the dosage may be gradually reduced. As atropine-like effects are absent, Colospa 135 mg is not contra-indicated in patients with glaucoma or prostatic hypertrophy. Store in a dry, dark place, at temperatures not exceeding 30°C. Keep out of reach of children.
Cautions Use with caution in: Failure of function of part of the gut causing an obstruction (paralytic ileus); Life long inherited blood diseases which can cause a variety of symptoms, including mental health problems (porphyrias). For women: Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine. This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than any possible risk to the foetus. Seek medical advice from your doctor. There are no known harmful effects when this medicine is used by breastfeeding mothers.
Possible side effects Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect. Constipation, confusion, agitation. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist. The safety of Colospa 135 mg in pregnancy has not been established.
If you take too much Known symptoms of overdosage and particulars of its treatment: none known.
Drug interactions Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.
Colofac, Generic Mebeverine DUPHAR
Category : Antispasmodic; smooth muscle relaxant. Mebeverine has a direct non-specific relaxant effect on vascular, cardiac, and other smooth muscle. Studies indicate that the spasmolytic activity of mebeverine is not restricted to one particular system, but the compound possesses a polyvalent spasmolytic action in which at least three types of mechanisms are involved:- a direct musculotropic action involving calcium ion exchange and stabilization of excitable membranes- a competitive antimuscarinic activity of about 0.05 - 0.1 times that of atropine- a local anaesthetic activity together with potentiation of sympathetic inhibitory influences due to blockade of noradrenaline uptake into sympathetic nerve endings
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Quality RX online pharmacy offers a discreet, low cost and reliable way to buy online prescription medications, generic drugs, herbal remedy and pet medication. Their online drug store provides discount proces on a wide selection of prescription drugs. What is the difference between Brands and Generics? Why do people prefer Generics? Generics are usually priced up to 80 percent less than equivalent brand-name versions. Why? Because brand-name drugs invest large amounts of money to advertise and persuade you to buy their product, Because generic manufacturers spend less on advertising and product development and because generic versions of the same medication create competition and competition can drive prices down. When the payment is confirmed by the bank, your order status transforms to “Pending”. Once the doctor approves your prescription, your order becomes “Approved”. All the orders are shipped within 1–2 business days. You should allow 5 – 9 days excl. weekends for a Fast shipping (express mail) and 12 – 16 days excl. weekends for a Standard shipping (regular mail). They do not have next day delivery. Quality RX don’t take orders by phone. According to their security privacy all the credit cards information must be typed by a customer only. That is why all the orders must be made directly via their official website. They accept Visa, American Express, JCB, Payment via Bank Account credit cards. They don't accept other forms of payments, such as paypal or bank transfer. How much do they charge for a doctor's consultation to write a prescription? There is no doctor’s consultation charge! Their doctor reviews orders for free. To minimize their customer’s costs, they cooperate with different suppliers, who have different sending options. That is why they may ship orders separate. It is important that if you make several orders within 24 hours, you pay for one delivery only, but in such cases they do not sum up medications costs for your next free delivery. How will the package arrive? Will people be able to tell its contents? All packages are shipped in plain packaging to protect your privacy. And they do not mention any costs on the package as well. Once you have ordered with their website and the order status transformed to “Shipped”, you get free bonus pills for all your next orders.

Pack Sizes for discount
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135mg 4 x 100 Tablets 135mg
100 Tablets 135mg 2 x 100 Tablets
135mg Tabs 30 (3 x 10)
Generic Name for Colospa: Mebeverine
Category for Colospa: Gastrointestinal

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all the credit cards information must be typed by a customer only. That is why
all the orders must be made directly via QualityRX official website.
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At this moment we accept Visa credit cards and payments via bank account. We
don't accept other forms of payments, such as Paypal or Western Union.
How much do you charge for a doctor's consultation to
write a prescription? There is no doctor’s consultation charge! Our doctor reviews
orders for free.
Why can't I order more than 1 medication at once? To
minimize out customer’s costs, we do cooperate with different suppliers, who
have different sending options. That is why we may ship orders separate. Important
is that if you make several orders within 24 hours, you pay for one delivery
only, but in such cases we do not sum up medications costs for your next free
delivery.
When do I get my order? When the payment is confirmed
by the bank, your order status transforms to “Pending”. Once the doctor approves
your prescription, your order becomes “Approved”. All the orders are shipped
within 1–2 business days. You should allow 5 – 9 days excl. weekends for a Fast
shipping (express mail) and 12 – 16 days excl. weekends for a Standard shipping
(regular mail). We do not have next day delivery.
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